Medieval Japan, the middle of the XV century.The country is burning civil war. A young warrior named Asitaka tribe Emishi sent into the woods of the great deity Sisigami to be cleansed from the curse, transformed him from a mad Kabanov God. It happened when Asitaka to save his village had to kill him. You must hurry up, curse slowlybut surely killing the young warrior. On the border of the forest he finds settlement steelmakers, led by charismatic eboshi - godzen. Cutting out the forests for steelmakers - a necessary element of the production cycle. They need fuel.Due to the metal they produce and produce from his firearms they can maintain independence from the surrounding lords. Settlement eboshi - shelter lepers and fugitives. People opposed to rational animals that inhabit the forest, and their deities headed goddess - she-wolf and her pupil - San, Printsessoy-Mononoke (" Mononoke " in Japanese - " an angry spirit"). And those and others to protect their interests. And neither one nor the other have nowhere to retreat. The third force in the conflict - the spies of the emperor, wishing to use the situation to get a head Sisigami, which, according to ancient legend, can give immortality to its owner. The heroism and betrayal,love and hate, eternal hostility and incipient trust again - this film has it all.